Our intervention study starts on 4 April 2025!

Conditions of participation:

You will be invited by e-mail if you

• have taken part in the screening;
• you are an early or late chronotype;
• you are studying at Paderborn University.

Unfortunately, you cannot participate if you

• Have not taken part in the screening
• You are an intermediate chronotype
• You regularly smoke and/or consume cannabis
• Leave all other points as they are

We would like to invite you to take part in a 180-minute intervention study to investigate how the glucose response to different sugar solutions with different glycaemic indices or different potential to trigger reactive hypoglycaemia affects memory performance.

In the intervention studies described here, we would now like to find out

• what effects a high GI breakfast has on memory performance in young healthy students (study 1)
• the effects of (isolated) reactive hypoglycaemia on memory performance in young healthy students (Study 2).

Effekte des glykämischen Index des Frühstücks und einer reaktiven Hypoglykämie auf den Verlauf von Gedächtnisleistung und Aufmerksamkeit bei jungen Erwachsenen - Relevanz des Chronotyps.

Wenn Ihr am Screening teilgenommen habt und wir feststellen konnten, dass Ihr eine typische Lerche oder Eule seid, werden wir Euch erneut kontaktieren und zu unseren Interventionsstudien 1 und 2 (kontrollierte Ernährungs- und Kognitionsstudie) einladen. Hier beschreiben wir kurz, was wir dann von Euch erbitten würden.

In diesen beiden Studien möchten wir herausfinden, welche Effekte Getränke mit hohem glykämischen Index und/oder einer (isolierten) reaktiven Hypoglykämie[1] auf die Gedächtnis- und Aufmerksamkeitsleistung bei Lerchen und Eulen haben.

Intervention studies 1 and 2 have the same procedure, differing only in the type of drink to be tested. The intervention study starts in April 2025.

The intervention studies each comprise 4 days of testing for each participant.

[1] Reactive hypoglycaemia, also known as postprandial hypoglycaemia, is a drop in blood glucose (blood sugar) to levels below the fasting value. This typically occurs within 1-3 hours after eating and is not related to diabetes. à Footnote (as before)

Week 1

• Preparation day (day 1) usually Friday
• Intervention day (day 2) usually Monday-Thursday

Week 2

• Preparation day (day 3) usually Friday
• Intervention day (day 4) usually Monday-Thursday

If the above-mentioned weekdays are public holidays, the respective day is moved forward by one day.

In the course of the studies, we ask you to carry out the following measurements or have them carried out:

• Anthropometric measurements including body composition (on preparation days),
• Fasting blood sampling from the vein (on preparation days),
• Continuous glucose measurement using a sensor that you wear on your stomach or upper arm (sensor will be placed on preparation days ),
• Determination of your activity and night-time rest phases on preparation days and intervention days using a sensor that you wear on your wrist
• Drinking a test drink (on intervention days)
• Repeated measurements of attention and memory performance over the course of 180 minutes (on intervention days)
• manual blood glucose measurement from the earlobe (on intervention days)
• repeated saliva samples (on intervention days)
• heart rate determination using a pulse belt (on intervention days)

If you take part in the controlled nutrition study,

• you will receive an expense allowance of up to €200 (€100 per intervention study),
• you will receive a dinner from us on the preparation days and a test meal (drink) on the intervention days,
• you will receive an evaluation of your activity and rest phases as an example for one day,
• you will receive feedback on your glucose profile on 2 study days,
• you will again find out the composition of your body (water, fat, muscle mass percentage), which we determine using bioelectrical impedance analysis.